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Half Of Top Cancer Studies Fail High-Profile Reproducibility Effort

By Asher Mullard writing for nature

Photo by Louis Reed on Unsplash

A US$2-million, 8-year attempt to replicate influential preclinical cancer research papers has released its final — and disquieting — results. Fewer than half of the experiments assessed stood up to scrutiny, reports the Reproducibility Project: Cancer Biology (RPCB) team in eLife1,2. The project — one of the most robust reproducibility studies performed so far — documented how hurdles including vague research protocols and uncooperative authors delayed the initiative by five years and halved its scope.

Read the full article on nature